The PhD Course Organization

Organization

The main research fields proposed in the curricula are here described.

 

Curriculum in Clinical and Aging Pathophysiology, Emergency Medicine and Nursing Sciences

Nursing Area

• Organ donation process in nursing sciences
• Clinical risk in nursing sciences
• Management of signs and symptoms of nursing competence

Medical Area

• Study of pathogenetic, clinical and therapeutic mechanisms and of the microbiota and its modulation in rare immunovascular, autoinflammatory and metabolic diseases of adults
• Pathophysiology, risk factors and antithrombotic therapies of atherothrombosis
• Pathophysiology, risk factors and antithrombotic therapies of venous thromboembolic disease
• Geriatric pathophysiology and epidemiology
• Pathophysiology and clinic of frailty and geriatric syndromes
• Aging of the vascular system and age-related diseases (cardiological, neurological, vascular): pathophysiology, clinic and rehabilitation
• Neurodegenerative diseases of the elderly: pathophysiology, clinic and rehabilitation
• Innovative social-health approaches for the care of the elderly and geriatric syndromes
• Innovative organizational models in Emergency Medicine
• Development of new advanced simulation methodologies to increase the efficiency/effectiveness of the trauma team

 

Curriculum in Clinical and Experimental Medicine and Radiology

• Biological bases (cellular, molecular, genetic, metabolic, microbiological, hormonal) of immune dysregulation and associated diseases (chronic inflammatory diseases, immunodeficiencies, autoimmunity, cancer)

• Biomarkers, phenotyping, sex and precision therapies in immune dysregulation diseases

• The role of new MRI (Diffusion, Perfusion) and CT (Perfusion with regard to dose reduction techniques in MultiSlice-CT and ConeBeam-CT) parameters in the evaluation of various anatomical districts (neuro and splanchnocranium; heart and thorax; abdomen and pelvis) pre and post therapy

• New Imaging techniques in the evaluation of microcirculation in fibrosing autoimmune diseases (skin, lung, musculoskeletal system)

• Radiomics

• Genetic basis and clinical-laboratory stratification of immunodeficiency common variable as a prototype of immune dysregulation disease: infections, autoimmunity and tumours

• Predisposing factors, pathophysiology, organ involvement and innovative therapeutic approaches in autoimmunity

• Predisposing factors, pathophysiology, and innovative therapeutic approaches in allergic diseases

• Predisposing factors, pathophysiology, and innovative therapeutic approaches in systemic fibrosing autoimmune diseases

• Study of the relationships between the immune system and the microbiota in the genesis of chronic inflammatory diseases and neoplasia

• Study of the intertumoral and peripheral immune response in solid tumors

• Translational aspects of chronic hepatopathies and primitive tumors of liver

• Cancer immunotherapy: strategies of treatment implementation and personalization

• Oncogenesis and biomarkers of neoplastic evolution secondary to hepatic viruses

• Translational and physiopathologic aspects of hepatic cirrhosis and portal hypertension

• Immunotherapy in autoimmunity and in rare immune-mediated diseases

• New classification approaches and organ involvement in rheumatic diseases

 

Curriculum in Pathology and Clinic of the Musculoskeletal System and Calcified Tissues

• Innovative methods of assisted orthopaedic surgery
• New biomaterials for orthopaedic and trauma surgery
• Analysis and evaluation of the interaction between biomaterials and bone in prosthetics and traumatology
• Tumor and pseudotumor pathologies of the musculoskeletal system
•  New technologies in osteoarticular reconstructions in orthopaedic surgery
• Mineral and bone metabolism in clinical models of calcified tissue diseases.
• Clinic of mineral and bone metabolism pathologies such as primary and secondary osteoporosis, osteomalacia and rare diseases of mineral and skeletal metabolism
• Translational studies in mineral and bone metabolism disorders
• Studies of analysis and intervention (nutritional, physiatric and pharmacological) for primary and secondary prevention of mineral and bone metabolism pathologies
• Technological innovation in the assessment and rehabilitation treatment of people with disabilities associated with musculoskeletal pathology
• Artificial intelligence applied to patient stratification and prediction of rehabilitation recovery in the field of musculoskeletal pathology
• Conservative and surgical orthopaedic treatments in rare diseases with musculoskeletal involvement
• Pathogenesis and therapy of periodontal and peri-implant disease
• New diagnostic methods of primary and secondary osteoporosis
• Non-pharmacological management of chronic pain syndromes.

 

Curriculum in Surgical Sciences

• New techniques and technologies in the field of general, urological, thoracic, cardiac, paediatric, and vascular surgery
•  Molecular precision medicine in the field of oncological pathology of surgical interest
•  Simulation in learning new techniques in the surgical field
•  Development of transplantation, from immunotherapy to surgery
• Application of minimally invasive surgery in urological oncology and pediatric urology
• Post-oncological and post-traumatic reconstructive surgery
• Morphological and bio-molecular study of cancers of urological interest (prostatic and urothelial cancers)
• Immunophenotype and genotype of adrenal and neural crest tumors: morphological and prognostic correlations

 

Curriculum in Psychology, Occupational Medicine, Anesthesiology and Pain Therapy

• Psychological and psychosocial mechanisms involved in the onset and/or maintenance of psychological distress, mental disorders, and physical illnesses, with particular reference to the bio-psycho-social model.
• Research methods in clinical and health psychology.
• Psychological interventions in psychological distress, mental disorders, and physical illness.
• Multidisciplinary approach to the study of anesthesiologic physiopathology and perioperative problems, with reference to subjects with cognitive and/or psychological frailty.
• Emerging risk factors in occupational medicine.

 

Curriculum in Infectious Diseases and International Cooperation, Global Health 

• Epidemiology, clinical and diagnostics of emerging and re-emerging infections as a global health problem
• Parasitosis and host response in endemic and non-endemic areas
• Vector-borne diseases and other emerging infections: One Health approach
• Antimicrobial resistance as a global problem: One Health approach
• Allergic diseases and bronchial asthma in mobile populations